Part V  by Frederick Goodwin and Kay Redfield Jamison, 2007 (Bold has been added to original text) p.203 Neurodevelopmental aspects of adolescent BP and the issue of puberty.  Many studies use the term “prepubertal” or pubertal” onset but the vast majority have neither verified the pubertal status of research participants …

Part IV  by Frederick Goodwin and Kay Redfield Jamison, 2007 (Bold has been added to original text) Adolescent – Onset Bipolar Disorder p. 196 The onset and first diagnosis of bipolar disorder frequently occur in adolescence. For the most part, adolescent-onset bipolar disorder is clinically similar to adult bipolar disorder.  …

Part III  by Frederick Goodwin and Kay Redfield Jamison, 2007 p. 194 Lack of Data and Insufficient Knowledge of Developmental issues. A further challenge to diagnosing BP in children is the limited utility of applying to this population features of adult BP symptoms and course. diagnostic confusion about how to …

Part II  by Frederick Goodwin and Kay Redfield Jamison, 2007 p. 190 Depressive Features   For many individuals bipolar disorder emerges in the form of depressive episodes in childhood. (Geller, Lish 1994). Although depression in children may be readily diagnoses using adult criteria, the majority of such cases probably go undetected …

Part I This excerpt is taken from the 2nd addition, 2007 two volume, 1000-page (with additional appendix and references) Manic-Depressive Illness – Bipolar Disorders and Recurrent Depression by Frederick Goodwin and Kay Redfield Jamison.  (Still available on Amazon or your nearest medical school library) This reference text is an exhaustive …

Hagop Akiskal (1944-2021) was an international giant of theory, research and clinical practice in Psychiatry during his 60-year career. He had collaborators on most continents and published hundreds of papers, dozens book chapters and was the originator and editor in chief for the Journal of Affective Disorders. Below is a …